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PHYTOGEN Interleukin Acne Inhibiting Factors
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The Only Proven Way to Naturally Clear Acne (Results published in National Institute of Health, US, 2019)
Researches show that acne can be inhibited
Topical products have been around for many years, mostly chemicals to eat away the top layer of the skin to stimulate re-growth, however, they can often cause more damage than good. Researches have found essential peptides that are effective in inhibiting certain proteins in the skin's amino acids in order to make the skin react in a different way to reduce the acne symptoms until they are eliminated naturally. With the extensive researches on Acne vulgaris for the past decades, what we now know is that Acne vulgaris is a very common chronic inflammatory disorder, yet its pathogenesis is not clearly understood. As part of the famous Mustard Gas-Exposed Patients: Sardasht-Iran Cohort Study (SICS), this study was conducted to evaluate the association between the incidence of acne vulgaris in SM-exposed subjects (20 years after the exposure) and serum levels of proinflammatory cytokines (IL-1α, IL-1β, IL-1Ra, IL-6, IL-8, IL-12 and RANTES) in an attempt to better understand the pathogenesis of long-term skin disorders of these individuals.
METHODS:
Serum concentrations of cytokines (IL-1α, IL-1β, IL-1Ra, IL-6, IL-8, IL-12 and RANTES) were measured using sandwich ELISA technique.
RESULTS:
The median of serum levels of IL-1β, IL-8 and RANTES were significantly higher in the exposed patients with acne than those without acne (P = 0.05, 0.03 and 0.001 respectively). There was no significant difference in serum levels of IL-1α, IL-1Ra and IL-6 between the exposed subgroups.
CONCLUSION:
They found a positive association between serum levels of pro-inflammatory cytokines (IL-1β, IL-8, IL-12 and RANTES) and acne among SM-exposed population.
What does this mean?
The above is only one of the many researches showing a definitive link between interleukin IL-1Ra and the inflammatory acne conditions, suggesting that people with pro-inflammatory cytokines IL-1β, IL-8, IL-12 and RANTES are living with acne vulgaris, and because IL-1Ra is a natural antagonist for the pro-inflammatory cytokines, it inhibits the acne inflammation.
Suitable for all types of acne conditions including chronic, hormonal, accidental, bacterial.
The Only Proven Way to Naturally Clear Acne (Results published in National Institute of Health, US, 2019)
Researches show that acne can be inhibited
Topical products have been around for many years, mostly chemicals to eat away the top layer of the skin to stimulate re-growth, however, they can often cause more damage than good. Researches have found essential peptides that are effective in inhibiting certain proteins in the skin's amino acids in order to make the skin react in a different way to reduce the acne symptoms until they are eliminated naturally. With the extensive researches on Acne vulgaris for the past decades, what we now know is that Acne vulgaris is a very common chronic inflammatory disorder, yet its pathogenesis is not clearly understood. As part of the famous Mustard Gas-Exposed Patients: Sardasht-Iran Cohort Study (SICS), this study was conducted to evaluate the association between the incidence of acne vulgaris in SM-exposed subjects (20 years after the exposure) and serum levels of proinflammatory cytokines (IL-1α, IL-1β, IL-1Ra, IL-6, IL-8, IL-12 and RANTES) in an attempt to better understand the pathogenesis of long-term skin disorders of these individuals.
METHODS:
Serum concentrations of cytokines (IL-1α, IL-1β, IL-1Ra, IL-6, IL-8, IL-12 and RANTES) were measured using sandwich ELISA technique.
RESULTS:
The median of serum levels of IL-1β, IL-8 and RANTES were significantly higher in the exposed patients with acne than those without acne (P = 0.05, 0.03 and 0.001 respectively). There was no significant difference in serum levels of IL-1α, IL-1Ra and IL-6 between the exposed subgroups.
CONCLUSION:
They found a positive association between serum levels of pro-inflammatory cytokines (IL-1β, IL-8, IL-12 and RANTES) and acne among SM-exposed population.
What does this mean?
The above is only one of the many researches showing a definitive link between interleukin IL-1Ra and the inflammatory acne conditions, suggesting that people with pro-inflammatory cytokines IL-1β, IL-8, IL-12 and RANTES are living with acne vulgaris, and because IL-1Ra is a natural antagonist for the pro-inflammatory cytokines, it inhibits the acne inflammation.